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Perimenopause May Be the Ideal Time for Cardiovascular Risk Prevention
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Perimenopause May Be the Ideal Time for Cardiovascular Risk Prevention

Healthline · May 23, 2026, 2:00 PM

Why this matters: health reporting relevant to everyday decisions and well-being.

Research shows that perimenopause may be the ideal time to adopt lifestyle changes to help lower cardiovascular risks. Image Credit: Aleksandar Nakic/Getty Images. A recent study suggests that perimenopause offers a “window of opportunity” for females to reassess cardiovascular risk and prompt lifestyle changes. The findings show that perimenopausal females may be two times more likely to have lower cardiovascular health scores. According to the study authors, lower cardiovascular health scores may be largely due to high cholesterol and blood sugar levels. Perimenopause is considered the transitional period leading up to menopause. During this time, the ovaries begin to gradually produce fewer hormones, particularly estrogen. According to a nationwide analysis, U.S. females experiencing perimenopause are twice as likely to have a low cardiovascular health score than those who are still regularly menstruating. The findings of this study were recently published in the Journal of the American Heart Association, a peer-reviewed journal of the American Heart Association (AHA). “From a cardiovascular standpoint, perimenopause is a very important time in which there are changing hormone levels, specifically with a declining estrogen level, which can have not only an impact on how one may feel but also on how one’s cardiovascular system is impacted and responds,” said Jossef Amirian, MD, a board certified cardiologist with Manhattan Cardiology in New York. Amirian wasn’t involved in the study. “The end result is potentially a change in body fat distribution, cholesterol and blood glucose levels, blood pressure, and this can all have an impact on blood flow and circulation as well,” he told Healthline. How perimenopause impacts cardiovascular health The analysis included data from 9,248 females ages 18 to 80 who participated in the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2020. The researchers used the AHA’s Life’s Essential 8 (

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