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STAT+: Otsuka kidney drug slowed loss of function, but less than expected, in late-stage trial
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STAT+: Otsuka kidney drug slowed loss of function, but less than expected, in late-stage trial

STAT News · Jun 4, 2026, 7:59 PM

Why this matters: health reporting relevant to everyday decisions and well-being.

Otsuka’s Voyxact slowed the loss of kidney function after one year in patients with a chronic autoimmune kidney disease, but the benefit was less than expected and left room for competing treatments to perform better.&#x A0; In a Phase 3 study, patients with Ig A nephropathy, or Ig AN, who received injections of Voyxact saw their kidneys lose function at an annualized rate of 3 points over one year compared to an annualized function loss of 7.6 points over one year for patients receiving a placebo, the Japanese drugmaker reported Thursday.  Kidney function was assessed with a lab test, called eGFR, that measures how well kidneys filter waste from the blood. Continue to STAT+ to read the full story…

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